Fluorobenzene is mainly used for the preparation of major raw materials such as the antipsychotic specific drug flucrobutanol, darokutane, trifluoperadinol, trifluoperadinobenzene, pentafluridol, and quinolone drug ciprofloxacin; At the same time, it is also used for the identification of pesticides, egg killers, plastics and resin polymers; Fluorobenzene and γ- The condensation of chlorobutyryl chloride can produce γ- Chloro-p-fluorobenzene butanone, used to synthesize haloperidol, is the most commonly used drug among butyrylbenzene antipsychotics. At present, fluorobenzene for medicine is the largest market segment of the fluorobenzene industry, accounting for about 65%. China is one of the major suppliers of the global fluorobenzene industry, and has strong influence in the global fluorobenzene industry.
In recent years, with the large-scale application in the chemical, pharmaceutical and agricultural industries, fluorobenzene is gradually showing huge market growth potential. In the pharmaceutical field, all kinds of pharmaceutical compounds need to use fluorobenzene in the synthesis process, so fluorobenzene is becoming more and more important, and its market scope is also expanding.
Fluorobenzene is mainly used in the production of raw materials in the pharmaceutical industry. The development trend shows that in the production process of pharmaceutical compounds, the market demand for aliphatic or aromatic fluorine-containing organic intermediates is becoming more and more common, and the proportion of pharmaceutical compounds in drug varieties is getting higher and higher. Fluorobenzene, as an important basic raw material of aromatic fluoride, has gradually improved its position in the pharmaceutical industry.
Fluorobenzene has strong stability, physiological activity, fat solubility and hydrophobicity, and can adjust electronic, lipophilic and other parameters. Therefore, many fluorobenzene containing drugs have the advantages of low dosage, low toxicity, high efficacy, strong metabolic capacity, etc. in terms of performance, which have a significant impact on the pharmacodynamics and pharmacokinetic properties of drugs. Due to the superior performance of fluorobenzene drugs, the research and development of fluorobenzene drugs have promoted the expansion of the domestic and foreign markets of fluorobenzene. At this stage, fluoroquinolones are the main application markets of fluorobenzene. Fluoroquinolones are a new class of anti infective drugs developed in the early 1970s. They have broad bactericidal spectrum, small side effects, and moderate prices. They are rapidly developing antibiotics in recent years.
Fluorobenzene is an important basic raw material in aromatic fluorides. Besides being used to synthesize medicines, pesticides and dyes, it can also further synthesize fluorobenzene derivatives for the above fields through nitration, chlorination, bromination, acylation, reduction and other reactions. In recent years, it has also been developed and used for the identification of resin polymers, thermoplastic engineering plastics, etc., with more and more applications and increasing market demand