Fosetyl-aluminium was developed by Rhone-Poulenc Co. in France in 1977.
Physical and chemical properties of Fosetyl-aluminium
Pure Fosetyl-aluminium is white crystal, odorless, and has a melting point higher than 300°C. The industrial product is white powder. The solubility in water at 20°C is 120 g/L, and it is difficult to dissolve in general organic solvents. Its solubility in acetonitrile and propylene glycol is less than 80 mg/L. Not easily volatile. The original drug and preparation are stable under normal storage conditions. It easily absorbs moisture and agglomerates, and does not affect the use effect after being crushed.
Fosetyl-aluminium is easily decomposed when exposed to strong acid and strong alkali. Low toxicity. The acute oral LD50 of rats is 5.8 g/kg, the acute oral LD50 of mice is 3.7~4.0 g/kg; the acute transdermal LD50 of rats is >3.2 g/kg, and the acute transdermal LD50 of mice is 4.0 g/kg. Rats and dogs were fed for 90 days, and the no-effect dose was 5.0 g/kg. The LC50 (96 hours) of rainbow trout, spotted fish and kingfish are 428 mg/L, 161 mg/L and 189 mg/L respectively. Safer for bees and wildlife. No irritation to human skin or eyes; non-corrosive. Within the test dose, no teratogenic or mutagenic effects were observed. It has a two-way internal suction conduction effect toward the top and base, and has both protective and therapeutic effects. It is active against Oomycete fungi, particularly effective against downy mildew, but less effective against anthrax.
Fosetyl-aluminium prevention and control objects and methods of use
Fosetyl-aluminium can be applied by spraying, watering the soil, dipping, etc. It is commonly used to control downy mildew and diseases caused by Phytophthora in vegetables, fruit trees, flowers and various economic crops. Spray 80% aluminum ethyl phosphorus wettable powder with 400 to 800 times of water to prevent downy mildew; water tobacco with about 90 times of water to prevent and control black shank; use 0.4% concentration of water with water to coat rubber tree tapping incisions to prevent canker disease . In order to avoid the continuous application of this product that will lead to the development of antibiotic resistance in bacteria and expand the targets of prevention and control, compound preparations are already available, such as (50% ethyl aluminum, 25% sterilant), (44% ethyl aluminum, 26% mancozeb), etc.
Precautions when using Fosetyl-aluminium
Fosetyl-aluminium is easy to react quickly when exposed to moisture, but this will not affect its efficacy. Therefore, Fosetyl-aluminiummust be stored in a cool, dry place. Unused Fosetyl-aluminium must be tightly tied. Place in a dry place.
When spraying, protective measures must be taken to prevent the liquid from splashing on exposed skin. If it is accidentally sprayed on the skin, it must be washed with clean water in time.
Do not wash utensils stained with chemicals into rivers, ponds and other water bodies to avoid causing water pollution; do not throw away used medicine bottles and dispose of them properly to prevent environmental pollution.
Fosetyl-aluminium cannot be mixed with alkaline pesticides. When using it, you must pay attention to the concentration to avoid losing the efficacy or causing phytotoxicity.